Modulating Brain Networks: Mechanisms, Models & Medical Translation

The symposium, organised by CRC1270 ELAINE and its IRTG, brings together leading experimentalists, clinicians, engineers and theoreticians to discuss how brain networks can be understood, modeled, and therapeutically modulated across scales and disease contexts. A particular focus lies on translational approaches linking fundamental mechanisms to clinical applications, including deep brain stimulation, closed-loop therapies, network biomarkers, and computational modeling. The symposium features a keynote lecture by Prof. Andreas Draguhn (Heidelberg) on intrinsic oscillations and the control of brain networks, and thematic sessions on a. CRC ELAINE platforms for network modulation, spanning electrophysiological biomarkers, micro-implants, disease models, and DBS modeling, b.Network modulation in neurological and neuropsychiatric diseases, including stroke, synucleinopathies, epilepsy, and SUDEP, c.Levers of network modulation, highlighting GABAergic mechanisms, interneuron microcircuits, stimulation strategies, and personalized closed-loop therapies.